http://globalhealthideas.org/2006/12/medical-innovation-for-hiv-prevention/ Sat, 26 Jun 2010 00:43:24 +0000 http://wordpress.org/?v=2.9.1 hourly 1 http://globalhealthideas.org/2006/12/medical-innovation-for-hiv-prevention/comment-page-1/#comment-246 bellows Thu, 21 Dec 2006 15:40:58 +0000 http://thdblog.wordpress.com/2006/12/14/medical-innovation-for-hiv-prevention/#comment-246 It'd be great to read the findings. The 2005 South African randomized control trial on male circumcision had strikingly positive results. I linked to their study above and here [Auvert, et al. 2005.<a href="http://medicine.plosjournals.org/perlserv?request=get-document&doi=10.1371/journal.pmed.0020298" rel="nofollow"> <i>PLoS</i>. "Randomized, Controlled Intervention Trial of Male Circumcision for Reduction of HIV Infection Risk: The ANRS 1265 Trial"</a>] There has been observational evidence accumulating since the 1990s that male circumcision is protective [see Halperin and Bailey, 1999, <i>Lancet</i>. <a href="http://www.circumcisioninfo.com/halperin_bailey.html" rel="nofollow">"Male circumcision and HIV infection: 10 years and counting"</a>] but these RCTs from last year and this past month are seen as conclusive evidence. There are interesting questions about the magnitude of the protective effect for pediatric versus late teen circumcision and additional reports on populations where the effect may not be observed will help in properly targeting the service as national circumcision programs are ramped up in the near future. It’d be great to read the findings. The 2005 South African randomized control trial on male circumcision had strikingly positive results. I linked to their study above and here [Auvert, et al. 2005. PLoS. "Randomized, Controlled Intervention Trial of Male Circumcision for Reduction of HIV Infection Risk: The ANRS 1265 Trial"] There has been observational evidence accumulating since the 1990s that male circumcision is protective [see Halperin and Bailey, 1999, Lancet. "Male circumcision and HIV infection: 10 years and counting"] but these RCTs from last year and this past month are seen as conclusive evidence. There are interesting questions about the magnitude of the protective effect for pediatric versus late teen circumcision and additional reports on populations where the effect may not be observed will help in properly targeting the service as national circumcision programs are ramped up in the near future.

]]> http://globalhealthideas.org/2006/12/medical-innovation-for-hiv-prevention/comment-page-1/#comment-245 Farzaneh Thu, 21 Dec 2006 10:12:30 +0000 http://thdblog.wordpress.com/2006/12/14/medical-innovation-for-hiv-prevention/#comment-245 Interestingly, in South Africa, you do not see the benefit from male circumcision on HIV transmission. This may be due to several factors, including the fact that many boys are sexually active before circumcision, which is part of the cultural initiation into manhood. Dr. Leickness Simbayi of the HSRC, who is a lead investigator on the South African National HIV Prevalence, HIV Incidence, Behaviour and Communication Survey, is writing up these findings for publication. Will post when the article is available. Interestingly, in South Africa, you do not see the benefit from male circumcision on HIV transmission. This may be due to several factors, including the fact that many boys are sexually active before circumcision, which is part of the cultural initiation into manhood. Dr. Leickness Simbayi of the HSRC, who is a lead investigator on the South African National HIV Prevalence, HIV Incidence, Behaviour and Communication Survey, is writing up these findings for publication. Will post when the article is available.

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